Microbial Mechanistic Insight into the Role of Yeast−Derived Postbiotics in Improving Sow Reproductive Performance in Late Gestation and Lactation Sows
Junlei Chang,
Xinlin Jia,
Yalei Liu,
Xuemei Jiang,
Lianqiang Che,
Yan Lin,
Yong Zhuo,
Bin Feng,
Zhengfeng Fang,
Jian Li,
Lun Hua,
Jianping Wang,
Zhihua Ren,
De Wu,
Shengyu Xu
Affiliations
Junlei Chang
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Xinlin Jia
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Yalei Liu
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Xuemei Jiang
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Lianqiang Che
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Yan Lin
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Yong Zhuo
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Bin Feng
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Zhengfeng Fang
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Jian Li
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Lun Hua
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Jianping Wang
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Zhihua Ren
Sichuan Province Key Laboratory of Animal Disease and Human Health, Key Laboratory of Environmental Hazard and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China
De Wu
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
Shengyu Xu
Key Laboratory for Animal Disease-Resistant Nutrition of China Ministry of Education, Ministry of Agriculture and Rural Affairs, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China
The purpose of this study is to investigate the effects of supplementing Yeast−derived postbiotics (Y−dP) to the diet of sows during late pregnancy and lactation on fecal microbiota and short−chain fatty acids (SCFA) in sows and their offspring weaned piglets, as well as the relationship between gut microbiota and SCFA, serum cytokines, and sow reproductive performance. A total of 150 sows were divided into three groups: control diet (CON), CON + Y−dP 1.25 g/kg, and CON + Y−dP 2 g/kg. The results showed that supplementing 0.125% Y−dP to the diet of sows can increase the content of isobutyric acid (IBA) in the feces of pregnant sows and reduce the content of butyric acid (BA) in the feces of weaned piglets (p p Limosilactobacilli in the feces of pregnant sows (p p 0.5, p Prevotellaceae_NK3B31_group was positively correlated with Acetic acid (AA), PA, Valerate acid (VA), and total volatile fatty acid (TVFA) in the feces of pregnant sows (r > 0.5, p Prevotellaceae_NK3B31_group were negatively correlated with the number of stillbirths (r p Lactobacillus and Holdemanella in piglet feces was positively correlated with TVFA in feces and negatively correlated with IgA in serum (r > 0.5, p Limosilactobacilli in the feces of sows during pregnancy, and increase the abundance of beneficial bacteria such as Bacteroidetes in piglet feces, thereby improving intestinal health. These findings provide a reference for the application of Y−dP in sow production and a theoretical basis for Y−dP to improve sow production performance.
