mSphere (Apr 2021)

Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model

  • Yuefei Jin,
  • Tiantian Sun,
  • Guangyuan Zhou,
  • Dong Li,
  • Shuaiyin Chen,
  • Weiguo Zhang,
  • Xueyuan Li,
  • Rongguang Zhang,
  • Haiyan Yang,
  • Guangcai Duan

DOI
https://doi.org/10.1128/mSphere.01048-20
Journal volume & issue
Vol. 6, no. 2

Abstract

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Enterovirus 71 (EV71) is associated with severe hand-foot-mouth disease. Recently, outbreaks of EV71 infection with high mortality have been reported in the Asia-Pacific region, posing a great challenge for global public health.