Unraveling the Molecular Landscape of SCN1A Gene Knockout in Cerebral Organoids: A Multiomics Approach Utilizing Proteomics, Lipidomics, and Transcriptomics

• Byumseok Koh,
• Young Eun Kim,
• Sung Bum Park,
• Seong Soon Kim,
• Jangjae Lee,
• Jeong Hyeon Jo,
• KyungJin Lee,
• Dong Hyuck Bae,
• Tae-Young Kim,
• Sung-Hee Cho,
• Myung Ae Bae,
• Dukjin Kang,
• Ki Young Kim

Affiliations

Byumseok Koh

Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

Young Eun Kim

Group for Biometrology, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea

Sung Bum Park

Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

Seong Soon Kim

Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

Jangjae Lee

Chemical Platform Technology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

Jeong Hyeon Jo

Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

KyungJin Lee

Department of Microbiology, CHA University School of Medicine, Seongnam, Republic of Korea

Dong Hyuck Bae

Department of Microbiology, CHA University School of Medicine, Seongnam, Republic of Korea

Tae-Young Kim

School of Earth Sciences & Environmental Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea

Sung-Hee Cho

Chemical Platform Technology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

Myung Ae Bae

Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea

Dukjin Kang

Group for Biometrology, Korea Research Institute of Standards and Science (KRISS), Daejeon, Republic of Korea

Ki Young Kim

Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea