Zhongguo youzhi (Mar 2024)
神经酸来源及分离方法的研究进展Research progress on sources and separation methods of nervonic acid
Abstract
神经酸是一种能够疏通、修复受损神经纤维和促进神经细胞再生的单不饱和脂肪酸,可用于预防及治疗脑萎缩、阿尔茨海默病等脑疾病,具有较高的药用价值。旨在为高纯度神经酸产品的生产和发展提供参考,综述了神经酸的功效和来源,详细阐述了植物来源神经酸的分离方法,包括其原理和特点。不同分离方法的耦合可克服单一分离方法的某些缺点,且一定程度上解决对神经酸纯度、产量双重提高的难题,成为重要的研究方向。Nervonic acid is a monounsaturated fatty acid that can unblock and repair damaged nerve fibers and promote nerve cell regeneration, so it can be used to prevent and treat brain diseases such as brain atrophy and Alzheimer′s disease, and has high medicinal value. In order to provide reference for the production and development of high-purity nervonic acid products, the efficacy and sources of nervonic acid were reviewed, and the separation methods of nervonic acid, including their principles and characteristics were described. The coupling of different methods can overcome some disadvantages of single separation method, solve the problem of improving the purity and yield of nervonic acid to a certain extent, which has become an important research direction for the separation of nervonic acid.
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