Nature Communications (Apr 2018)

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

  • Chunming Ding,
  • Yen Ching Lim,
  • Sook Yoong Chia,
  • Arcinas Camille Esther Walet,
  • Shaohai Xu,
  • Kinyui Alice Lo,
  • Yanling Zhao,
  • Dewen Zhu,
  • Zhihui Shan,
  • Qingfeng Chen,
  • Melvin Khee-Shing Leow,
  • Dan Xu,
  • Lei Sun

DOI
https://doi.org/10.1038/s41467-018-03754-3
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

Read online

Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and subcutaneous white adipose tissues.