Cancer-Associated Thrombosis: Beyond Clinical Practice Guidelines—A Multidisciplinary (SEMI–SEOM–SETH) Expert Consensus
Vanessa Pachón,
Javier Trujillo-Santos,
Pere Domènech,
Enrique Gallardo,
Carmen Font,
José Ramón González-Porras,
Pedro Pérez-Segura,
Ana Maestre,
José Mateo,
Andrés Muñoz,
María Luisa Peris,
Ramón Lecumberri
Affiliations
Vanessa Pachón
Department of Oncology, Hospital Universitario Ramón y Cajal, Madrid, Spain
Javier Trujillo-Santos
Department of Internal Medicine, Hospital Universitario Santa Lucía, Cartagena, Spain
Pere Domènech
Thrombosis and Haemostasis Unit, Hospital Universitario Bellvitge, L'Hospitalet de Llobregat, Catalonia, Spain
Enrique Gallardo
Department of Oncology, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Spain
Carmen Font
Department of Medical Oncology, Hospital Clinic, Barcelona, Spain
José Ramón González-Porras
Hematology Service, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain
Pedro Pérez-Segura
Department of Oncology, Hospital Clínico San Carlos, Madrid, Spain
Ana Maestre
Department of Internal Medicine, Hospital del Vinalopó, Elche, Spain
José Mateo
Hematology Service, Hospital Santa Creu i Sant Pau, Barcelona, Spain
Andrés Muñoz
Department of Oncology, Hospital Universitario Gregorio Marañón, Madrid, Spain
María Luisa Peris
Department of Internal Medicine, Hospital Provincial de Castellón, Castellón, Spain
Ramón Lecumberri
Hematology Service, Clínica Universidad de Navarra, IDISNA, CIBER-CV, Pamplona, Spain
Despite the growing interest and improved knowledge about venous thromboembolism in cancer patients in the last years, there are still many unsolved issues. Due to the limitations of the available literature, evidence-based clinical practice guidelines are not able to give solid recommendations for challenging scenarios often present in the setting of cancer-associated thrombosis (CAT). A multidisciplinary expert panel from three scientific societies—Spanish Society of Internal Medicine (SEMI), Spanish Society of Medical Oncology (SEOM), and Spanish Society Thrombosis and Haemostasis (SETH)—agreed on 12 controversial questions regarding prevention and management of CAT, which were thoroughly reviewed to provide further guidance. The suggestions presented herein may facilitate clinical decisions in specific complex circumstances, until these can be made leaning on reliable scientific evidence.
