NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections

Philippe Rascle; Cyril Planchais; Béatrice Jacquelin; Marie Lazzerini; Vanessa Contreras; Caroline Passaes; Asier Saez-Cirion; Hugo Mouquet; Nicolas Huot; Michaela Müller-Trutwin

doi:10.1038/s42003-022-03619-y

Communications Biology (Jul 2022)

NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infections

Philippe Rascle,
Cyril Planchais,
Béatrice Jacquelin,
Marie Lazzerini,
Vanessa Contreras,
Caroline Passaes,
Asier Saez-Cirion,
Hugo Mouquet,
Nicolas Huot,
Michaela Müller-Trutwin

Affiliations

Philippe Rascle: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris
Cyril Planchais: Institut Pasteur, Laboratory of Humoral Immunology, Université de Paris
Béatrice Jacquelin: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris
Marie Lazzerini: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris
Vanessa Contreras: CEA, Université Paris Sud 11, INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases, IDMIT, IBFJ
Caroline Passaes: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris
Asier Saez-Cirion: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris
Hugo Mouquet: Institut Pasteur, Laboratory of Humoral Immunology, Université de Paris
Nicolas Huot: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris
Michaela Müller-Trutwin: Institut Pasteur, Unité HIV Inflammation and Persistance, Université de Paris

DOI: https://doi.org/10.1038/s42003-022-03619-y
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

Read online

Differences between pathogenic and non-pathogenic SIV infections are investigated, in terms of NK cell location, function and IgA responses in gut associated lymphoid tissues (mesenteric lymph nodes, jejunum, ileon, colon).

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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