Nature Communications (Nov 2020)
Viral rhodopsins 1 are an unique family of light-gated cation channels
- Dmitrii Zabelskii,
- Alexey Alekseev,
- Kirill Kovalev,
- Vladan Rankovic,
- Taras Balandin,
- Dmytro Soloviov,
- Dmitry Bratanov,
- Ekaterina Savelyeva,
- Elizaveta Podolyak,
- Dmytro Volkov,
- Svetlana Vaganova,
- Roman Astashkin,
- Igor Chizhov,
- Natalia Yutin,
- Maksim Rulev,
- Alexander Popov,
- Ana-Sofia Eria-Oliveira,
- Tatiana Rokitskaya,
- Thomas Mager,
- Yuri Antonenko,
- Riccardo Rosselli,
- Grigoriy Armeev,
- Konstantin Shaitan,
- Michel Vivaudou,
- Georg Büldt,
- Andrey Rogachev,
- Francisco Rodriguez-Valera,
- Mikhail Kirpichnikov,
- Tobias Moser,
- Andreas Offenhäusser,
- Dieter Willbold,
- Eugene Koonin,
- Ernst Bamberg,
- Valentin Gordeliy
Affiliations
- Dmitrii Zabelskii
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Alexey Alekseev
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Kirill Kovalev
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Vladan Rankovic
- Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen
- Taras Balandin
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Dmytro Soloviov
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Dmitry Bratanov
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Ekaterina Savelyeva
- Institute of Biological Information Processing (IBI-3: Bioelectronics), Forschungszentrum Jülich GmbH
- Elizaveta Podolyak
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Dmytro Volkov
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Svetlana Vaganova
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Roman Astashkin
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Igor Chizhov
- Institute for Biophysical Chemistry, Hannover Medical School
- Natalia Yutin
- National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
- Maksim Rulev
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Alexander Popov
- European Synchrotron Radiation Facility
- Ana-Sofia Eria-Oliveira
- Institut de Biologie Structurale (IBS), Université Grenoble Alpes, CEA, CNRS
- Tatiana Rokitskaya
- Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University
- Thomas Mager
- Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen
- Yuri Antonenko
- Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University
- Riccardo Rosselli
- Evolutionary Genomics Group, Departamento de Producción Vegetal y Microbiología, Universidad Miguel Hernández
- Grigoriy Armeev
- Biological Faculty, M. V. Lomonosov Moscow State University
- Konstantin Shaitan
- Biological Faculty, M. V. Lomonosov Moscow State University
- Michel Vivaudou
- Institut de Biologie Structurale (IBS), Université Grenoble Alpes, CEA, CNRS
- Georg Büldt
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Andrey Rogachev
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Francisco Rodriguez-Valera
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Mikhail Kirpichnikov
- Biological Faculty, M. V. Lomonosov Moscow State University
- Tobias Moser
- Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen
- Andreas Offenhäusser
- Institute of Biological Information Processing (IBI-3: Bioelectronics), Forschungszentrum Jülich GmbH
- Dieter Willbold
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- Eugene Koonin
- National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
- Ernst Bamberg
- Research Center for Molecular Mechanisms of Aging and Age-related Diseases, Moscow Institute of Physics and Technology
- Valentin Gordeliy
- Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich GmbH
- DOI
- https://doi.org/10.1038/s41467-020-19457-7
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 16
Abstract
Nucleocytoplasmic Large DNA Viruses (NCLDV) that infect algae encode two distinct families of microbial rhodopsins. Here, the authors characterise two proteins form the viral rhodopsin group 1 OLPVR1 and VirChR1, present the 1.4 Å crystal structure of OLPVR1 and show that viral rhodopsins 1 are light-gated cation channels.
