Nature Communications (May 2021)

Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals

  • Yan Li,
  • Aymeric Leveau,
  • Qiang Zhao,
  • Qi Feng,
  • Hengyun Lu,
  • Jiashun Miao,
  • Zheyong Xue,
  • Azahara C. Martin,
  • Eva Wegel,
  • Jing Wang,
  • Anastasia Orme,
  • Maria-Dolores Rey,
  • Miroslava Karafiátová,
  • Jan Vrána,
  • Burkhard Steuernagel,
  • Ryan Joynson,
  • Charlotte Owen,
  • James Reed,
  • Thomas Louveau,
  • Michael J. Stephenson,
  • Lei Zhang,
  • Xuehui Huang,
  • Tao Huang,
  • Danling Fan,
  • Congcong Zhou,
  • Qilin Tian,
  • Wenjun Li,
  • Yiqi Lu,
  • Jiaying Chen,
  • Yan Zhao,
  • Ying Lu,
  • Chuanrang Zhu,
  • Zhenhua Liu,
  • Guy Polturak,
  • Rebecca Casson,
  • Lionel Hill,
  • Graham Moore,
  • Rachel Melton,
  • Neil Hall,
  • Brande B. H. Wulff,
  • Jaroslav Doležel,
  • Tim Langdon,
  • Bin Han,
  • Anne Osbourn

DOI
https://doi.org/10.1038/s41467-021-22920-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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The genomic organization and origin of the avenacin biosynthetic gene cluster remain unknown. Here, the authors assemble the genome of diploid oat Avena strigosa, reveal the structure and organization of the consecutive genes, characterize the last two missing pathway steps, and investigate the origin of the pathway in cereals.