Nature Communications (Jan 2019)

A viral expression factor behaves as a prion

  • Hao Nan,
  • Hongying Chen,
  • Mick F. Tuite,
  • Xiaodong Xu

DOI
https://doi.org/10.1038/s41467-018-08180-z
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Prion-forming proteins have been found in animals, plants, fungi, and bacteria. Here, Nan et al. report that a baculovirus-encoded protein behaves as prion in a yeast system and forms aggregates at high multiplicity of infection in insect cells that affect baculovirus replication.