Nature Communications (Dec 2021)

Influence of the chirality of carbon nanodots on their interaction with proteins and cells

  • Huijie Yan,
  • Michele Cacioppo,
  • Saad Megahed,
  • Francesca Arcudi,
  • Luka Đorđević,
  • Dingcheng Zhu,
  • Florian Schulz,
  • Maurizio Prato,
  • Wolfgang J. Parak,
  • Neus Feliu

DOI
https://doi.org/10.1038/s41467-021-27406-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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Chirality is known to impact the biological activity of materials but concentration differences can often lead to errors in analysis. Here, the authors report on detailed concertation analysis of different chiral carbon nanodots to accurately investigate chiral effects on the protein absorption and cell internalisation.