Development and Validation of Zero-field NMR Spectrometer Based on Compact Atomic Magnetometer

FU Fangyue; GUO Qingqian; FENG Xiaoyu; XU Jiayu; YAO Zekun; HU Tao; YANG Xiaodong; CHANG Yan

doi:10.11938/cjmr20233060

Chinese Journal of Magnetic Resonance (Mar 2024)

Development and Validation of Zero-field NMR Spectrometer Based on Compact Atomic Magnetometer

FU Fangyue,
GUO Qingqian,
FENG Xiaoyu,
XU Jiayu,
YAO Zekun,
HU Tao,
YANG Xiaodong,
CHANG Yan

Affiliations

FU Fangyue: 1. School of Electronic and Information Engineering, Changchun University of Science and Technology, Changchun 130022, China 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
GUO Qingqian: 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China 3. Jihua Laboratory, Foshan 528200, China
FENG Xiaoyu: 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China 3. Jihua Laboratory, Foshan 528200, China
XU Jiayu: 1. School of Electronic and Information Engineering, Changchun University of Science and Technology, Changchun 130022, China 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
YAO Zekun: 1. School of Electronic and Information Engineering, Changchun University of Science and Technology, Changchun 130022, China 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
HU Tao: 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China 3. Jihua Laboratory, Foshan 528200, China 4. Jinan Guoke Medical Technology Development Co., Ltd, Jinan 250101, China
YANG Xiaodong: 1. School of Electronic and Information Engineering, Changchun University of Science and Technology, Changchun 130022, China 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
CHANG Yan: 1. School of Electronic and Information Engineering, Changchun University of Science and Technology, Changchun 130022, China 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China 3. Jihua Laboratory, Foshan 528200, China

DOI: https://doi.org/10.11938/cjmr20233060
Journal volume & issue: Vol. 41, no. 1
pp. 87 – 98

Abstract

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Conventional high-field nuclear magnetic resonance (NMR) spectrometer necessitates advanced superconducting technology, which usually involves a magnet of large volume and high maintenance cost. Moreover, strong magnet often has severe magnetic field inhomogeneity, leading to NMR line broadening. Zero- to ultralow-field (ZULF) NMR emerged as a complementary approach to traditional high-field NMR techniques. In this paper, a portable zero-field NMR spectrometer based on a compact atomic magnetometer was developed, which adopted an integrated control system based on a multi-function data acquisition card (National Instruments PCIe-6353). The spectrometer is of a main magnetic field strength less than 1 nT and enables achieving high-resolution J-spectrum under zero-field environment. Specifically, a series of single pulse excitation experiments for the initial adiabatic state was carried out to calibrate the triaxial magnetic field coils. Then a modified composite pulse sequence was developed to further validate the performance of zero-field NMR spectrometer by single-spin control experiments for the 13C-1H spin system.

Published in Chinese Journal of Magnetic Resonance

ISSN: 1000-4556 (Print)
Publisher: Science Press
Country of publisher: China
LCC subjects: Science: Physics: Electricity and magnetism
Website: http://121.43.60.238/bpxzz/EN/1000-4556/home.shtml

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