Local generation of hydrogen for enhanced photothermal therapy

Penghe Zhao; Zhaokui Jin; Qian Chen; Tian Yang; Danyang Chen; Jin Meng; Xifeng Lu; Zhen Gu; Qianjun He

doi:10.1038/s41467-018-06630-2

Nature Communications (Oct 2018)

Local generation of hydrogen for enhanced photothermal therapy

Penghe Zhao,
Zhaokui Jin,
Qian Chen,
Tian Yang,
Danyang Chen,
Jin Meng,
Xifeng Lu,
Zhen Gu,
Qianjun He

Affiliations

Penghe Zhao: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University
Zhaokui Jin: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University
Qian Chen: Department of Bioengineering, University of California, Los Angeles
Tian Yang: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University
Danyang Chen: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University
Jin Meng: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University
Xifeng Lu: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University
Zhen Gu: Department of Bioengineering, University of California, Los Angeles
Qianjun He: Guangdong Provincial Key Laboratory of Biomedicalim Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Health Science Center, Shenzhen University

DOI: https://doi.org/10.1038/s41467-018-06630-2
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 12

Abstract

Read online

The tracking and targeted release of multi-agents to cooperatively treat cancer is a developing and evolving field. Here, the authors demonstrate the anticancer effects of cubic Pd hydride nanocrystals with photoacoustic imaging properties that can release hydrogen under an NIR trigger and have photothermal effects.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal