Correlation between CT Abdominal Anthropometric Measurements and Liver Density in Individuals with Non-Alcoholic Fatty Liver Disease
Dragoș Constantin Cucoranu,
Marian Pop,
Raluca Niculescu,
Vlad Vunvulea,
Irina-Bianca Kosovski,
Radu-Ovidiu Togănel,
Eliza Russu,
Adrian Vasile Mureșan,
Răzvan-Andrei Licu,
Anca Bacârea
Affiliations
Dragoș Constantin Cucoranu
Department of Radiology, Mures County Emergency Hospital, 540136 Targu Mures, Romania
Marian Pop
ME1 Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
Raluca Niculescu
Pathology Department, Mures Clinical County Hospital, 540011 Targu Mures, Romania
Vlad Vunvulea
Department of Radiology, Mures County Emergency Hospital, 540136 Targu Mures, Romania
Irina-Bianca Kosovski
Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
Radu-Ovidiu Togănel
Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 38 Gheorghe Marinescu Street, 540139 Targu Mures, Romania
Eliza Russu
Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania
Adrian Vasile Mureșan
Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania
Răzvan-Andrei Licu
Department of Radiology, Mures County Emergency Hospital, 540136 Targu Mures, Romania
Anca Bacârea
Pathophysiology Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
Background: With a growing frequency, nonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. NAFLD has a strong correlation with other metabolic disorders, such as obesity, particularly abdominal obesity, even though the underlying causes or risk factors are not entirely understood. This study aims to investigate correlations between abdominal anthropometric measurements and the presence and intensity of liver steatosis as assessed by unenhanced computed tomography (CT). Methods: One hundred and nineteen patients (male/female, 66/53; mean age 54.54 +/− 12.90 years) underwent abdominal non–contrast-enhanced CT. CT images were examined to determine the attenuation of liver parenchyma, subcutaneous fat depth, and waist circumference (WC). Results: Among all patients, WC (r = −0.78, p p p p p = 0.04), WC (OR: 11.45, p p p = 0.01), and infraumbilical (OR: 3.06, p = 0.007) were strongly independent predictors of NAFLD risk. Moreover, regarding the laboratory parameters, only the higher value of GGT (OR: 2.84, p = 0.009) is a predictor of NAFLD risk. Conclusions: Our data show that higher baseline values of all abdominal anthropometric measurements are correlated with liver attenuation and act as predictors of NAFLD risk.
