Impact of diet and host genetics on the murine intestinal mycobiome

Yask Gupta; Anna Lara Ernst; Artem Vorobyev; Foteini Beltsiou; Detlef Zillikens; Katja Bieber; Simone Sanna-Cherchi; Angela M. Christiano; Christian D. Sadik; Ralf J. Ludwig; Tanya Sezin

doi:10.1038/s41467-023-36479-z

Nature Communications (Feb 2023)

Impact of diet and host genetics on the murine intestinal mycobiome

Yask Gupta,
Anna Lara Ernst,
Artem Vorobyev,
Foteini Beltsiou,
Detlef Zillikens,
Katja Bieber,
Simone Sanna-Cherchi,
Angela M. Christiano,
Christian D. Sadik,
Ralf J. Ludwig,
Tanya Sezin

Affiliations

Yask Gupta: Lübeck Institute of Experimental Dermatology, University of Lübeck
Anna Lara Ernst: Lübeck Institute of Experimental Dermatology, University of Lübeck
Artem Vorobyev: Lübeck Institute of Experimental Dermatology, University of Lübeck
Foteini Beltsiou: Lübeck Institute of Experimental Dermatology, University of Lübeck
Detlef Zillikens: Department of Dermatology, University of Lübeck
Katja Bieber: Lübeck Institute of Experimental Dermatology, University of Lübeck
Simone Sanna-Cherchi: Division of Nephrology, Department of Medicine, Columbia University Irving Medical Center
Angela M. Christiano: Department of Dermatology, Columbia University Irving Medical Center
Christian D. Sadik: Department of Dermatology, University of Lübeck
Ralf J. Ludwig: Lübeck Institute of Experimental Dermatology, University of Lübeck
Tanya Sezin: Department of Dermatology, University of Lübeck

DOI: https://doi.org/10.1038/s41467-023-36479-z
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 17

Abstract

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In this study, 591 mice from an advanced-intercross mouse line were used to provide evidence that fungi are regulated by host genetics, while uncovering a regulatory role of diet on the composition of fungi in the murine gut.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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