Investigation of Triazavirin Antiviral Activity Against Tick-Borne Encephalitis Pathogen in Cell Culture

S. YA. Loginova; S. V. Borisevich; V. L. Rusinov; U. N. Ulomsky; V. N. Charushin; O. N. Chupakhin

Антибиотики и Химиотерапия (May 2020)

Investigation of Triazavirin Antiviral Activity Against Tick-Borne Encephalitis Pathogen in Cell Culture

S. YA. Loginova,
S. V. Borisevich,
V. L. Rusinov,
U. N. Ulomsky,
V. N. Charushin,
O. N. Chupakhin

Affiliations

S. YA. Loginova: Central Research Institute No. 33, Ministry of Defense of the Russian Federation
S. V. Borisevich: Central Research Institute No. 33, Ministry of Defense of the Russian Federation
V. L. Rusinov: B.N. Eltsin Urals State Technical University, Ekaterinburg
U. N. Ulomsky: B.N. Eltsin Urals State Technical University, Ekaterinburg
V. N. Charushin: B.N. Eltsin Urals State Technical University, Ekaterinburg
O. N. Chupakhin: B.N. Eltsin Urals State Technical University, Ekaterinburg

Journal volume & issue: Vol. 59, no. 1-2
pp. 3 – 5

Abstract

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The efficacy of Triazavirin against the tick-borne encephalitis virus was estimated in the sensitive cell culture vs. the active drug Ribavirin®. In a concentration of 128 mcg/ml Triazavirin was shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.

Published in Антибиотики и Химиотерапия

ISSN: 0235-2990 (Print)
Publisher: LLC "Publishing House OKI"
Country of publisher: Russian Federation
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.antibiotics-chemotherapy.ru/

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Abstract

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