BIO Web of Conferences (Jan 2023)

Antitumor Effects and Mechanisms of Snake Venom: A Systematic Review

  • Hu Jianguo,
  • Dapar Mark Lloyd G.

DOI
https://doi.org/10.1051/bioconf/20236002012
Journal volume & issue
Vol. 60
p. 02012

Abstract

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Snake venom, as a natural biotoxin, is widely present in nature and can act in coordination with a variety of signal regulatory proteins, playing a significant role in the regulation of tumor cell proliferation, metastasis, invasion, and angiogenesis. Malignant tumors have long attracted the attention of the medical community as the leading cause of death in humans. In this paper, we focus on reviewing the progress of snake venom in the regulation of apoptosis, proliferation, metastasis, invasion, and angiogenesis of tumor cells in malignant tumors in order to clarify the mechanisms by which snake venom suppresses malignant tumors and to provide a reference for the study of malignant tumors.