eMIONs: novel genetically engineered nanocages for magnetic hyperthermia cancer therapy

Abstract

The clinical introduction of magnetic hyperthermia therapy (MHT) has been hindered by current available agents with poor magnetic-to-thermal conversion efficiency and biocompatibility. It is believed that the genetically engineered magnetic nanocages of encapsulin-produced magnetic iron oxide nanocomposites (eMIONs) have great potential as clinically translatable MHT agents for cancer magneto-catalytic theranostics.

Keywords

• magnetic hyperthermia therapy
• nanocages
• iron oxide nanoparticles
• biomineralization