Molecules (Aug 2025)

Medicinal Plants for Skin Disorders: Phytochemistry and Pharmacological Insights

  • Nazerke Bolatkyzy,
  • Daniil Shepilov,
  • Rakhymzhan Turmanov,
  • Dmitriy Berillo,
  • Tursunay Vassilina,
  • Nailya Ibragimova,
  • Gulzat Berganayeva,
  • Moldyr Dyusebaeva

DOI
https://doi.org/10.3390/molecules30153281
Journal volume & issue
Vol. 30, no. 15
p. 3281

Abstract

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Skin disorders are common and often chronic conditions with significant therapeutic challenges. Limitations of conventional treatments, such as adverse effects and antimicrobial resistance, have increased interest in plant-based alternatives. This article presents the phytochemical composition and pharmacological potential of several medicinal plants traditionally used in the treatment of skin diseases, including Rubus vulgaris, Plantago major, Artemisia terrae-albae, and Eryngium planum. Based on an analysis of scientific literature, the presence of bioactive compounds—including flavonoids, anthocyanins, phenolic acids, tannins, and sesquiterpenes—is summarized, along with their antioxidant, anti-inflammatory, and antimicrobial effects. Emphasis is placed on the correlation between traditional ethnomedicinal applications and pharmacological mechanisms. The findings support the potential of these species as sources for dermatological phytotherapeutics. Further research is needed to standardize active constituents, assess safety, and conduct clinical validation.

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