Nature Communications (Apr 2020)
The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia
- Matthias I. Gröschel,
- Conor J. Meehan,
- Ivan Barilar,
- Margo Diricks,
- Aitor Gonzaga,
- Matthias Steglich,
- Oscar Conchillo-Solé,
- Isabell-Christin Scherer,
- Uwe Mamat,
- Christian F. Luz,
- Katrien De Bruyne,
- Christian Utpatel,
- Daniel Yero,
- Isidre Gibert,
- Xavier Daura,
- Stefanie Kampmeier,
- Nurdyana Abdul Rahman,
- Michael Kresken,
- Tjip S. van der Werf,
- Ifey Alio,
- Wolfgang R. Streit,
- Kai Zhou,
- Thomas Schwartz,
- John W. A. Rossen,
- Maha R. Farhat,
- Ulrich E. Schaible,
- Ulrich Nübel,
- Jan Rupp,
- Joerg Steinmann,
- Stefan Niemann,
- Thomas A. Kohl
Affiliations
- Matthias I. Gröschel
- Molecular and Experimental Mycobacteriology, Research Center Borstel
- Conor J. Meehan
- School of Chemistry and Bioscience, University of Bradford
- Ivan Barilar
- Molecular and Experimental Mycobacteriology, Research Center Borstel
- Margo Diricks
- bioMérieux, Applied Maths NV, Keistraat 120
- Aitor Gonzaga
- Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures
- Matthias Steglich
- Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures
- Oscar Conchillo-Solé
- Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona
- Isabell-Christin Scherer
- Department of Infectious Diseases and Microbiology, University Hospital Schleswig-Holstein
- Uwe Mamat
- Cellular Microbiology, Research Center Borstel
- Christian F. Luz
- Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, University of Groningen
- Katrien De Bruyne
- bioMérieux, Applied Maths NV, Keistraat 120
- Christian Utpatel
- Molecular and Experimental Mycobacteriology, Research Center Borstel
- Daniel Yero
- Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona
- Isidre Gibert
- Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona
- Xavier Daura
- Institute of Biotechnology and Biomedicine, Universitat Autònoma de Barcelona
- Stefanie Kampmeier
- Institute of Hygiene, University Hospital Münster
- Nurdyana Abdul Rahman
- Department of Microbiology, Singapore General Hospital
- Michael Kresken
- Antiinfectives Intelligence GmbH
- Tjip S. van der Werf
- Department of Pulmonary Diseases & Tuberculosis, University Medical Center Groningen, University of Groningen
- Ifey Alio
- Department of Microbiology and Biotechnology, University of Hamburg
- Wolfgang R. Streit
- Department of Microbiology and Biotechnology, University of Hamburg
- Kai Zhou
- Shenzhen Institute of Respiratory Diseases, the First Affiliated Hospital (Shenzhen People’s Hospital), Southern University of Science and Technology
- Thomas Schwartz
- Karlsruhe Institute of Technology, Institute of Functional Interfaces
- John W. A. Rossen
- Department of Medical Microbiology and Infection Prevention, University Medical Center Groningen, University of Groningen
- Maha R. Farhat
- Department of Biomedical Informatics, Harvard Medical School
- Ulrich E. Schaible
- Cellular Microbiology, Research Center Borstel
- Ulrich Nübel
- Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures
- Jan Rupp
- Department of Infectious Diseases and Microbiology, University Hospital Schleswig-Holstein
- Joerg Steinmann
- Institute of Medical Microbiology, University Medical Center Essen
- Stefan Niemann
- Molecular and Experimental Mycobacteriology, Research Center Borstel
- Thomas A. Kohl
- Molecular and Experimental Mycobacteriology, Research Center Borstel
- DOI
- https://doi.org/10.1038/s41467-020-15123-0
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 12
Abstract
Multidrug resistance of the opportunistic pathogen Stenotrophomonas maltophilia is an increasing problem. Here, analyzing strains from 22 countries, the authors show that the S. maltophilia complex is divided into 23 monophyletic lineages and find evidence for intra-hospital transmission.
