Nature Communications (Jun 2020)

CRISPR artificial splicing factors

  • Menghan Du,
  • Nathaniel Jillette,
  • Jacqueline Jufen Zhu,
  • Sheng Li,
  • Albert Wu Cheng

DOI
https://doi.org/10.1038/s41467-020-16806-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Control over splicing could be used for both therapeutic and engineering applications. Here the authors create artificial splicing factors using RNA-targeting CRISPR systems under small molecule control.