Treatment of parry-romberg syndrome and linear scleroderma en coup de sabre, with application of poly-L-lactic acid (PLLA): assessment of clinical response and high-resolution ultrasonography

Abstract

INTRODUCTION: Parry-Romberg syndrome and linear scleroderma en coup de sabre are disorders within the scleroderma spectrum, a disease that presents therapeutic challenges. OBJECTIVES: We treated three patients with this condition using poly-L-lactic acid (PLLA) with the aim of alleviating facial asymmetries and evaluated the real improvement of scleroderma lesions with high-resolution ultrasound. METHODS: The patients underwent two to four sessions of biostimulation with PLLA over a 12-month period. RESULTS: The results were promising, demonstrating favorable cosmetic outcomes with increased thickness of the dermis and hypodermis as evidenced by high-resolution ultrasound. CONCLUSIONS: Biostimulation with PLLA is a safe and effective treatment option for these patients when administered by trained professionals.

Keywords

• facial hemiatrophy
• scleroderma, localized
• dermal fillers
• ultrasonography