Nature Communications (Feb 2016)
Genomic insights into the Ixodes scapularis tick vector of Lyme disease
- Monika Gulia-Nuss,
- Andrew B. Nuss,
- Jason M. Meyer,
- Daniel E. Sonenshine,
- R. Michael Roe,
- Robert M. Waterhouse,
- David B. Sattelle,
- José de la Fuente,
- Jose M. Ribeiro,
- Karine Megy,
- Jyothi Thimmapuram,
- Jason R. Miller,
- Brian P. Walenz,
- Sergey Koren,
- Jessica B. Hostetler,
- Mathangi Thiagarajan,
- Vinita S. Joardar,
- Linda I. Hannick,
- Shelby Bidwell,
- Martin P. Hammond,
- Sarah Young,
- Qiandong Zeng,
- Jenica L. Abrudan,
- Francisca C. Almeida,
- Nieves Ayllón,
- Ketaki Bhide,
- Brooke W. Bissinger,
- Elena Bonzon-Kulichenko,
- Steven D. Buckingham,
- Daniel R. Caffrey,
- Melissa J. Caimano,
- Vincent Croset,
- Timothy Driscoll,
- Don Gilbert,
- Joseph J. Gillespie,
- Gloria I. Giraldo-Calderón,
- Jeffrey M. Grabowski,
- David Jiang,
- Sayed M. S. Khalil,
- Donghun Kim,
- Katherine M. Kocan,
- Juraj Koči,
- Richard J. Kuhn,
- Timothy J. Kurtti,
- Kristin Lees,
- Emma G. Lang,
- Ryan C. Kennedy,
- Hyeogsun Kwon,
- Rushika Perera,
- Yumin Qi,
- Justin D. Radolf,
- Joyce M. Sakamoto,
- Alejandro Sánchez-Gracia,
- Maiara S. Severo,
- Neal Silverman,
- Ladislav Šimo,
- Marta Tojo,
- Cristian Tornador,
- Janice P. Van Zee,
- Jesús Vázquez,
- Filipe G. Vieira,
- Margarita Villar,
- Adam R. Wespiser,
- Yunlong Yang,
- Jiwei Zhu,
- Peter Arensburger,
- Patricia V. Pietrantonio,
- Stephen C. Barker,
- Renfu Shao,
- Evgeny M. Zdobnov,
- Frank Hauser,
- Cornelis J. P. Grimmelikhuijzen,
- Yoonseong Park,
- Julio Rozas,
- Richard Benton,
- Joao H. F. Pedra,
- David R. Nelson,
- Maria F. Unger,
- Jose M. C. Tubio,
- Zhijian Tu,
- Hugh M. Robertson,
- Martin Shumway,
- Granger Sutton,
- Jennifer R. Wortman,
- Daniel Lawson,
- Stephen K. Wikel,
- Vishvanath M. Nene,
- Claire M. Fraser,
- Frank H. Collins,
- Bruce Birren,
- Karen E. Nelson,
- Elisabet Caler,
- Catherine A. Hill
Affiliations
- Monika Gulia-Nuss
- Department of Entomology, Purdue University
- Andrew B. Nuss
- Department of Entomology, Purdue University
- Jason M. Meyer
- Department of Entomology, Purdue University
- Daniel E. Sonenshine
- Department of Biological Sciences, Old Dominion University
- R. Michael Roe
- Department of Entomology, North Carolina State University
- Robert M. Waterhouse
- Department of Genetic Medicine and Development, University of Geneva Medical School
- David B. Sattelle
- UCL Respiratory Department, Division of Medicine, Centre for Respiratory Biology, University College London
- José de la Fuente
- SaBio, Instituto de Investigación en Recursos Cinegéticos, IREC-CSIC-UCLM-JCCM, Ronda de Toledo sn
- Jose M. Ribeiro
- Laboratory of Malaria and Vector Research, NIAID
- Karine Megy
- VectorBase/EMBL-EBI, Wellcome Trust Genome Campus
- Jyothi Thimmapuram
- Bioinformatics Core, Purdue University
- Jason R. Miller
- J. Craig Venter Institute
- Brian P. Walenz
- J. Craig Venter Institute
- Sergey Koren
- J. Craig Venter Institute
- Jessica B. Hostetler
- J. Craig Venter Institute
- Mathangi Thiagarajan
- J. Craig Venter Institute
- Vinita S. Joardar
- J. Craig Venter Institute
- Linda I. Hannick
- J. Craig Venter Institute
- Shelby Bidwell
- J. Craig Venter Institute
- Martin P. Hammond
- VectorBase/EMBL-EBI, Wellcome Trust Genome Campus
- Sarah Young
- Genome Sequencing and Analysis Program, Broad Institute
- Qiandong Zeng
- Genome Sequencing and Analysis Program, Broad Institute
- Jenica L. Abrudan
- Department of Biological Sciences, University of Notre Dame
- Francisca C. Almeida
- Departament de Genètica & Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona
- Nieves Ayllón
- SaBio, Instituto de Investigación en Recursos Cinegéticos, IREC-CSIC-UCLM-JCCM, Ronda de Toledo sn
- Ketaki Bhide
- Bioinformatics Core, Purdue University
- Brooke W. Bissinger
- Department of Entomology, North Carolina State University
- Elena Bonzon-Kulichenko
- Vascular Physiopathology, Centro Nacional de Investigaciones Cardiovasculares
- Steven D. Buckingham
- UCL Respiratory Department, Division of Medicine, Centre for Respiratory Biology, University College London
- Daniel R. Caffrey
- Department of Medicine, Division of Infectious Diseases, University of Massachusetts Medical School
- Melissa J. Caimano
- Department of Medicine, University of Connecticut Health Center
- Vincent Croset
- Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne
- Timothy Driscoll
- Genetics, Bioinformatics, and Computational Biology Program, Virginia Bioinformatics Institute at Virginia Tech
- Don Gilbert
- Department of Biology, Indiana University
- Joseph J. Gillespie
- Genetics, Bioinformatics, and Computational Biology Program, Virginia Bioinformatics Institute at Virginia Tech
- Gloria I. Giraldo-Calderón
- Department of Entomology, Purdue University
- Jeffrey M. Grabowski
- Department of Entomology, Purdue University
- David Jiang
- Department of Biochemistry, Virginia Tech
- Sayed M. S. Khalil
- Department of Microbial Molecular Biology, Agricultural Genetic Engineering Research Institute
- Donghun Kim
- Department of Entomology, Texas A&M University
- Katherine M. Kocan
- Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University
- Juraj Koči
- Department of Entomology, Kansas State University
- Richard J. Kuhn
- Department Biological Sciences, Markey Center for Structural Biology, Purdue University
- Timothy J. Kurtti
- Department of Entomology, University of Minnesota
- Kristin Lees
- Department of Neurosystems, Faculty of Life Sciences, University of Manchester
- Emma G. Lang
- Department of Entomology, Purdue University
- Ryan C. Kennedy
- Department of Bioengineering and Therapeutic Sciences, University of California
- Hyeogsun Kwon
- Department of Entomology, Texas A&M University
- Rushika Perera
- Department Biological Sciences, Markey Center for Structural Biology, Purdue University
- Yumin Qi
- Department of Biochemistry, Virginia Tech
- Justin D. Radolf
- Department of Medicine, University of Connecticut Health Center
- Joyce M. Sakamoto
- Department of Entomology, The Pennsylvania State University
- Alejandro Sánchez-Gracia
- Departament de Genètica & Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona
- Maiara S. Severo
- Department of Entomology, Center for Disease Vector Research, University of California
- Neal Silverman
- Department of Medicine, Division of Infectious Diseases, University of Massachusetts Medical School
- Ladislav Šimo
- Department of Entomology, Kansas State University
- Marta Tojo
- Department of Pathology, Cambridge Genomic Services, University of Cambridge
- Cristian Tornador
- Department of Experimental and Health Sciences, Universidad Pompeu Fabra
- Janice P. Van Zee
- Department of Entomology, Purdue University
- Jesús Vázquez
- Vascular Physiopathology, Centro Nacional de Investigaciones Cardiovasculares
- Filipe G. Vieira
- Departament de Genètica & Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona
- Margarita Villar
- SaBio, Instituto de Investigación en Recursos Cinegéticos, IREC-CSIC-UCLM-JCCM, Ronda de Toledo sn
- Adam R. Wespiser
- Department of Medicine, Division of Infectious Diseases, University of Massachusetts Medical School
- Yunlong Yang
- Department of Entomology, Texas A&M University
- Jiwei Zhu
- Department of Entomology, North Carolina State University
- Peter Arensburger
- Department of Biological Sciences, California State Polytechnic University
- Patricia V. Pietrantonio
- Department of Entomology, Texas A&M University
- Stephen C. Barker
- Parasitology Section, School of Chemistry & Molecular Biosciences, University of Queensland
- Renfu Shao
- GeneCology Research Centre, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast
- Evgeny M. Zdobnov
- Department of Genetic Medicine and Development, University of Geneva Medical School
- Frank Hauser
- Department of Biology, Center for Functional and Comparative Insect Genomics, University of Copenhagen
- Cornelis J. P. Grimmelikhuijzen
- Department of Biology, Center for Functional and Comparative Insect Genomics, University of Copenhagen
- Yoonseong Park
- Department of Entomology, Kansas State University
- Julio Rozas
- Departament de Genètica & Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona
- Richard Benton
- Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne
- Joao H. F. Pedra
- Department of Entomology, Center for Disease Vector Research, University of California
- David R. Nelson
- Department of Microbiology, Immunology & Biochemistry, University of Tennessee Health Science Center
- Maria F. Unger
- Department of Biological Sciences, University of Notre Dame
- Jose M. C. Tubio
- Cancer Genome Project, Wellcome Trust Sanger Institute
- Zhijian Tu
- Department of Biochemistry, Virginia Tech
- Hugh M. Robertson
- Department of Entomology, University of Illinois at Urbana-Champaign
- Martin Shumway
- J. Craig Venter Institute
- Granger Sutton
- J. Craig Venter Institute
- Jennifer R. Wortman
- J. Craig Venter Institute
- Daniel Lawson
- VectorBase/EMBL-EBI, Wellcome Trust Genome Campus
- Stephen K. Wikel
- Department of Medical Sciences, Frank H. Netter MD School of Medicine at Quinnipiac University
- Vishvanath M. Nene
- J. Craig Venter Institute
- Claire M. Fraser
- Institute for Genome Sciences, University of Maryland, School of Medicine
- Frank H. Collins
- Department of Biological Sciences, University of Notre Dame
- Bruce Birren
- The Broad Institute of MIT and Harvard
- Karen E. Nelson
- J. Craig Venter Institute
- Elisabet Caler
- J. Craig Venter Institute
- Catherine A. Hill
- Department of Entomology, Purdue University
- DOI
- https://doi.org/10.1038/ncomms10507
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 13
Abstract
Ticks transmit a large number of pathogens that cause human diseases. Here, the authors sequence the genome of the tick Ixodes scapularisand uncover expansion of genes associated with parasitic processes unique to ticks and tick-host interactions.
