Brazilian Journal of Radiation Sciences (Feb 2024)

Development of alternative methodology for normalization of the small animals PET scanner of LIM/CDTN

  • Anna Clara Moreira da Silva,
  • Victória Garcia Moreira,
  • Bruno Melo Mendes,
  • Rodrigo Modesto Gadelha Gontijo,
  • Andrea Vidal Ferreira

DOI
https://doi.org/10.15392/2319-0612.2024.2360
Journal volume & issue
Vol. 12, no. 1

Abstract

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Normalization is a step taken to correct variations in count rates between detection channels of small animals PET scanners. In general, in laboratory practice, normalization is performed using a commercial source of germanium 68. Given the half-life of the Ge-68 isotope, the normalization source must be replaced every two years at most, which generates a significant spent for the Laboratory. The objective of this work was to develop and test an alternative rechargeable source to be used on normalization routine. The results indicated that the rechargeable source (18F-FDG) can be used to replace the commercial source.

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