Nature Communications (Oct 2019)

Photoactivation of silicon rhodamines via a light-induced protonation

  • Michelle S. Frei,
  • Philipp Hoess,
  • Marko Lampe,
  • Bianca Nijmeijer,
  • Moritz Kueblbeck,
  • Jan Ellenberg,
  • Hubert Wadepohl,
  • Jonas Ries,
  • Stefan Pitsch,
  • Luc Reymond,
  • Kai Johnsson

DOI
https://doi.org/10.1038/s41467-019-12480-3
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Activatable fluorophores are of interest for a wide range of applications but the need for caging groups complicates their development and application. Here, the authors report on a photoactivatable silicon rhodamine derivative and its application in live cell imaging and single-particle tracking.