Primary small cell neuroendocrine carcinoma of the urinary bladder

Abstract

Primary small cell neuroendocrine carcinomas of the urinary bladder are rare, highly aggressive tumors and diagnosed mainly at advanced stages. Herein, we report a case of a 75-year-old man who presented with acute urinary retention and was found to have an infiltrative growth in the bladder. Histopathology and immunohistochemistry (IHC) were diagnostic of primary small cell neuroendocrine carcinoma. This case is being presented because of its rarity and highlighting the importance of histopathology and IHC in differentiating clinical mimics and making accurate diagnosis.

Keywords

• Immunohistochemistry
• primary neuroendocrine carcinoma
• urinary bladder