Nature Communications (Aug 2021)

The regulatory impact of RNA-binding proteins on microRNA targeting

  • Sukjun Kim,
  • Soyoung Kim,
  • Hee Ryung Chang,
  • Doyeon Kim,
  • Junehee Park,
  • Narae Son,
  • Joori Park,
  • Minhyuk Yoon,
  • Gwangung Chae,
  • Young-Kook Kim,
  • V. Narry Kim,
  • Yoon Ki Kim,
  • Jin-Wu Nam,
  • Chanseok Shin,
  • Daehyun Baek

DOI
https://doi.org/10.1038/s41467-021-25078-5
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.