Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies

• Rashi Gupta,
• Rashi Gupta,
• Emma Vanlieshout,
• Emma Vanlieshout,
• Kieran Manion,
• Dennisse Bonilla,
• Michael Kim,
• Carolina Muñoz-Grajales,
• Carolina Muñoz-Grajales,
• Carol Nassar,
• Carol Nassar,
• Sindhu R. Johnson,
• Sindhu R. Johnson,
• Linda T. Hiraki,
• Zareen Ahmad,
• Zareen Ahmad,
• Zahi Touma,
• Zahi Touma,
• Arthur Bookman,
• Arthur Bookman,
• Joan E. Wither,
• Joan E. Wither,
• Joan E. Wither,
• Joan E. Wither

Affiliations

Rashi Gupta

Department of Immunology, University of Toronto, Toronto, ON, Canada

Rashi Gupta

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Emma Vanlieshout

Department of Immunology, University of Toronto, Toronto, ON, Canada

Emma Vanlieshout

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Kieran Manion

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Dennisse Bonilla

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Michael Kim

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Carolina Muñoz-Grajales

Department of Immunology, University of Toronto, Toronto, ON, Canada

Carolina Muñoz-Grajales

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Carol Nassar

Department of Immunology, University of Toronto, Toronto, ON, Canada

Carol Nassar

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Sindhu R. Johnson

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada

Sindhu R. Johnson

Toronto Scleroderma Program, Department of Medicine, Toronto Western and Mount Sinai Hospitals, University of Toronto, Toronto, ON, Canada

Linda T. Hiraki

The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Toronto, ON, Canada

Zareen Ahmad

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada

Zareen Ahmad

Toronto Scleroderma Program, Department of Medicine, Toronto Western and Mount Sinai Hospitals, University of Toronto, Toronto, ON, Canada

Zahi Touma

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada

Zahi Touma

University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada

Arthur Bookman

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada

Arthur Bookman

Division of Rheumatology, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada

Joan E. Wither

Department of Immunology, University of Toronto, Toronto, ON, Canada

Joan E. Wither

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada

Joan E. Wither

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada

Joan E. Wither

Division of Rheumatology, Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada