Advances in Cyclodextrins and Their Derivatives in Nano-Delivery Systems
Xin-Yu Ji,
Yi-Xuan Zou,
Han-Fang Lei,
Yong Bi,
Rui Yang,
Ji-Hui Tang,
Qing-Ri Jin
Affiliations
Xin-Yu Ji
School of Pharmacy, Hangzhou Medical College, Hangzhou 310053, China
Yi-Xuan Zou
National institute of Metrology, Beijing 100029, China
Han-Fang Lei
College of Pharmacy, Anhui Medical University, Hefei 230032, China
Yong Bi
College of Pharmacy, Anhui Medical University, Hefei 230032, China
Rui Yang
NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, National Institutes for Food and Drug Control, Beijing 100050, China
Ji-Hui Tang
College of Pharmacy, Anhui Medical University, Hefei 230032, China
Qing-Ri Jin
School of Pharmacy, Hangzhou Medical College, Hangzhou 310053, China
The diversity of cyclodextrins and their derivatives is increasing with continuous research. In addition to monomolecular cyclodextrins with different branched chains, cyclodextrin-based polymers have emerged. The aim of this review is to summarize these innovations, with a special focus on the study of applications of cyclodextrins and their derivatives in nano-delivery systems. The areas covered include nanospheres, nano-sponges, nanogels, cyclodextrin metal–organic frameworks, liposomes, and emulsions, providing a comprehensive and in-depth understanding of the design and development of nano-delivery systems.
