Microbiologia Medica (Jun 2006)

Sieroepidemiologia delle infezioni da Toxoplasma gondii, virus della Rosolia e Citomegalovirus in una coorte di gravide

  • Marco Moretti,
  • Barbara Pieretti,
  • Simonetta Gasperoni,
  • Nicoletta Gambini,
  • Gabriele Canucoli,
  • Mario Casini,
  • Tiziana Temellini,
  • Alfredo Vaccaro,
  • Massimo Agostini,
  • Ernesto Delprete

DOI
https://doi.org/10.4081/mm.2006.2936
Journal volume & issue
Vol. 21, no. 2

Abstract

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Toxoplasma gondii, Rubella virus and Citomegalovirus are responsible for maternal-fetal infections that can cause severe consequences in fetus. The surveillance of these infections in pregnancy is made by specific antibodies detection and when necessary by demostrating the presence of the infectious agent in body fluids. We have evaluated the seroprevalence of antibodies in a cohort of 1100 pregnant women against Toxoplasma gondii, Rubella virus and Citomegalovirus. Our data show a low seroprevalence against Toxoplasma gondii, a suboptimal immunitary coverage against Rubella virus and a significative increase of incidence in Citomegalovirus infection. The study suggests the need of a multiprofessional and multidisciplinary approach for the right management of these maternal-fetal infections and underlines the pivot role played by Clinical Pathologists.

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