Association between metabolic syndrome and Helicobacter pylori infection: A myth or a fact? A cross-sectional study

Abstract

Aim: To determine the association between Helicobacter pylori and metabolic syndrome. Methods: This study comprised 31 study subjects whose biopsies were positive for H. pylori. Fasting plasma glucose (FPG), body mass index, serum triglycerides, serum high-density lipoprotein (HDL), and blood pressure were estimated in this group. Abnormalities in at least three of the five parameters were considered to be metabolic syndrome. Results: The results showed a significant association between H. pylori and metabolic syndrome, based on P = 0.007 (<0.05) in the Chi-square test. There was also an insignificant correlation between sex and metabolic syndrome (P = 0.576). A large percentage of the study group had high FPG (67.74%), low serum HDL (77.42%), and hypertension (87.10%). 78.2% of the study group had metabolic syndrome. Conclusion: The present study suggests that H. pylori gastritis is significantly associated with metabolic syndrome. It is recommended to do further research using a larger sample size to explore the relationship between Metabolic syndrome and H. pylori infection. The H. pylori eradication can be used as a tool in the prevention and treatment of metabolic syndrome.

Keywords

• body mass index
• high-density lipoprotein
• helicobacter pylori
• metabolic syndrome