Syringocystadenocarcinoma Papilliferum in the Perianal Area

Abstract

Syringocystadenocarcinoma papilliferum (SCACP) is a very rare cutaneous adnexal neoplasm. SCACP presents histologic variability, and it is difficult to establish the diagnosis from a punch biopsy. SCACP has an overall configuration similar to that of syringocystadenoma papilliferum (SCAP). When we diagnose SCACP, the histologic features of SCAP can be contributing and immunohistochemical staining is useful. Our case shows the histologic variability of SCACP and the pitfalls of a punch biopsy for the diagnosis of SCACP.

Keywords

• Lymph node metastasis
• Adenocarcinoma
• Syringocystadenocarcinoma papilliferum
• Perianal syringocystadenocarcinoma papilliferum
• Pagetoid spread
• Cutaneous adnexal neoplasm
• Perianal area