Фармакокинетика и Фармакодинамика (Jun 2021)

Study the subchronic toxicity of the drug Dantinorm Baby

  • A. V. Sorokina,
  • S. V. Alekseeva,
  • I. A. Miroshkina,
  • K. S. Kachalov,
  • A. D. Zaharov,
  • I. V. Alekseev,
  • A. S. Lapizkaya

DOI
https://doi.org/10.37489/2587-7836-2020-3-52-60
Journal volume & issue
Vol. 0, no. 3
pp. 52 – 60

Abstract

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Presents results of a study of subchronic toxicity of homeopathic drug Dantinorm Baby in finished dosage form. The drug in the form of a ready solution was administered daily orally for one month to outbred rats Infanta and chinchilla rabbits at a dose of 0.3 ml/kg, corresponding to the therapeutic, and 3 ml/kg, exceeding the therapeutic dose 10 times. Clinical, laboratory and histopathological studies performed in accordance with the General Protocol, showed no toxic effects of homeopathic preparation of Dantinorm Baby. The totality of the obtained data of the subchronic experiment indicates that there are no obstacles to the clinical study of the drug Dantinorm Baby in the range of therapeutic dosages.

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