Identification of DICER1 Syndrome on the Basis of Familial, Early‐Onset Differentiated Thyroid Cancer

Abstract

ABSTRACT DICER1 syndrome encompasses a wide range of phenotypes, and not all individuals with DICER1 syndrome develop aggressive soft tissue tumors. DICER1 syndrome and other genetic conditions predisposing to the development of thyroid tumors should be considered when a young patient presents with thyroid nodules and a positive family history.

Keywords

• adolescent
• genetic predisposition to disease
• genetic testing
• thyroid neoplasms