Skin abscess caused by Trueperella bernardiae: Case report and literature review
Rasha M. Abddelgader,
Sarvenaz Karamooz,
Hosoon Choi,
Munok Hwang,
Chetan Jinadatha,
Dhammika H. Navarathna
Affiliations
Rasha M. Abddelgader
Department of Pathology and Laboratory Medicine, Baylor Scott & White Medical Center, Temple, TX, USA
Sarvenaz Karamooz
Department of Pathology and Laboratory Medicine, Baylor Scott & White Medical Center, Temple, TX, USA
Hosoon Choi
Department of Research, Central Texas Veterans Health Care System, Temple, TX, USA
Munok Hwang
Department of Research, Central Texas Veterans Health Care System, Temple, TX, USA
Chetan Jinadatha
Department of Research, Central Texas Veterans Health Care System, Temple, TX, USA; Department of Medicine, Central Texas Veterans Health Care System, Temple, TX, USA
Dhammika H. Navarathna
Department of Pathology and Laboratory Medicine Services, Central Texas Veterans Health Care System, Temple, TX, USA; Correspondence to: Bldg.163 Department of Pathology and Lab. Medicine, 1901 Veterans Memorial, Temple, TX 76504, USA.
We investigated a skin abscess caused by Trueperella bernardiae in a patient with comorbidities. Initial empirical therapy with Clindamycin did not yield a response, and follow-up culture revealed the presence of T. bernardiae through MALDI-TOF and NGS. Since no CLSI or FDA breakpoints have been published for this strain, resistant gene screening of the genetic sequence showed the presence of the erm(X) gene (with 95 % identity). This gene confers resistance to erythromycin, clindamycin, lincomycin, pristinamycin, quinupristin, and virginiamycin. Subsequent therapy with oral amoxicillin/clavulanate led to complete healing.
