STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN

Abstract

Experimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigated for studying of the antibiotic stability, when azithromycin is used in wet granulation tableting technology. Identifies the main technological characteristics of the granulates, the tablets are produced by compression and indicators of quality are studied.

Keywords

• azithromycin
• excipients
• granulation
• antimicrobial activity
• oro-dispersible tablets