Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease

Sen H. M.; Silan F.; Degirmenci Y.; Kamaran Ozisik H. I.

doi:10.2478/bjmg-2014-0072

Balkan Journal of Medical Genetics (Dec 2014)

Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease

Sen H. M.,
Silan F.,
Degirmenci Y.,
Kamaran Ozisik H. I.

Affiliations

Sen H. M.: Department of Neurology, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Barboros Mah., Terzioğlu Kampüsü, Tıp Fakültesi, Çanakkale, Turkey. Tel : +90-286-218-37-38. Fax : +90-286-218-00-18.
Silan F.: Department of Medical Genetics, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Çanakkale, Turkey
Degirmenci Y.: Department of Pharmacology, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Çanakkale, Turkey
Kamaran Ozisik H. I.: Department of Neurology, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Çanakkale, Turkey

DOI: https://doi.org/10.2478/bjmg-2014-0072
Journal volume & issue: Vol. 17, no. 2
pp. 37 – 41

Abstract

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The CY2C19 and P2Y12 gene polymorphisms are responsible for resistance to clopidogrel, known as drug unresponsiveness. In this study we researched the effect of gene polymorphism on clinical results of patients who began clopidogrel therapy after acute ischemic cerebrovascular disease.

Published in Balkan Journal of Medical Genetics

ISSN: 1311-0160 (Print); 2199-5761 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Science: Biology (General): Genetics
Website: https://sciendo.com/journal/BJMG

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Abstract

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