Inhibitory action of a macrolide antibiotic, roxithromycin,
 on co-stimulatory molecule expressions in vitro and in vivo

Affiliations

Mayumi Suzuki: Department of Otolaryngology, School of Medicine, Showa University, Shinagawa-ku, Tokyo 142–8555, Japan
Kazuhito Asano: Department of Physiology, School of Medicine, Showa University, Shinagawa-ku, Tokyo 142–8555, Japan
Mei Yu: Department of Otolaryngology, School of Medicine, Showa University, Shinagawa-ku, Tokyo 142–8555, Japan
Tadashi Hisamitsu: Department of Physiology, School of Medicine, Showa University, Shinagawa-ku, Tokyo 142–8555, Japan
Harumi Suzaki: Department of Otolaryngology, School of Medicine, Showa University, Shinagawa-ku, Tokyo 142–8555, Japan

Abstract

Objective: The influence of a macrolide antibiotic, roxithromycin (RXM), on co-stimulatory molecule expression was examined in vitro and in vivo.