Cephalosporin-associated biliary pseudolithiasis in children

Abstract

The review presents current data about cephalosporin-associated biliary sludge and cholelithiasis formation mechanism. Risks factors of pseudolithiasis development in children, who received cephalosporins, are analyzed and systematized. Moreover, the study provides information about the prevalence of pseudolithiasis in different periods of childhood. Not only main ways of ceftriaxone-induced cholelithiasis clinical course, but also the most common complications of pseudolithiasis have been described. The report characterizes typical clinical symptoms and sonographic features of pseudolithiasis in children. Furthermore, the research considers main methods of treatment that allow to avoid unnecessary cholecystectomy in children. For writing the review, we used such databases, as Scopus, Web of Science, MedLine, PubMed, Google Scholar, CyberLeninka, RSCI.

Keywords

• cephalosporins
• biliary cholelithiasis
• children
• review