Nature Communications (Nov 2022)

CLIMB: High-dimensional association detection in large scale genomic data

  • Hillary Koch,
  • Cheryl A. Keller,
  • Guanjue Xiang,
  • Belinda Giardine,
  • Feipeng Zhang,
  • Yicheng Wang,
  • Ross C. Hardison,
  • Qunhua Li

DOI
https://doi.org/10.1038/s41467-022-34360-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

Read online

Comparisons among experimental results with large amounts of data can be more precise and meaningful when done across multiple different conditions simultaneously. Koch et al. introduce a method, called CLIMB, that does this, and captures interpretable and biologically meaningful information.