Exploratory Animal and Medical Research (Aug 2022)

SURVEILLANCE OF CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA FROM ANIMAL SOURCES IN MATHURA REGION, UTTAR PRADESH, INDIA

  • A. Arun,
  • U. Jaiswal ,
  • S. Tripathi ,
  • A. P. Singh ,
  • S. Choudhury,
  • S. N. Prabhu

DOI
https://doi.org/10.52635/eamr/12.1.91-98
Journal volume & issue
Vol. 12, no. 1
pp. 91 – 98

Abstract

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A cross-sectional study was conducted to determine the prevalence of Carbapenem-resistant Gram-negative bacteria (CR-GNB) in animals. The study involves one hundred eighty-four GNB isolates from 214 samples (feces, milk, pus, and uterine discharge) from Buffalo (N=112), Cattle (N=50), and Dog (N=52). Healthy and diseased animals reported to Veterinary Clinical Complex were sampled. Carbapenemase production was evaluated by phenotypic methods and the presence of Metallo β-lactamase genes was assayed by PCR. We observed a 9.78% overall prevalence of CR-GNB in animal sources. CR-GNB was more frequently recovered from companion animals (19.23%) when compared to livestock (4.93%). IMP (44.4%), VIM (38.8%), and OXA-48 (16.66 %) were the main MBLs observed in the study.

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