An Epidemiological Study of Acute Poisoning In a Tertiary Care Centre

Abstract

Introduction: Acute poisoning represents a real health threat in the world. It is a common cause of admission to emergency department and in intensive care unit. Periodic clinical and epidemiological studies are required to understand the pattern of poisoning. This study aims to analyze epidemiological aspect, clinical profile, and outcome of acute poisoning in a tertiary care hospital. Material and Methods: A cross sectional study was conducted at Government Medical College Hospital, Kota, Rajasthan. 102 admitted patients were taken for study from January 2020 to August 2020. Epidemiological variables age, sex, type of poison, mode of exposure, clinical presentation and outcome were studied. Results: The median age was 30.23 years with a male predominance (54.9%). The circumstances of poisoning were suicidal, accidental and unknown in 88.2%, 9.8%, and 1.96% respectively. Ingestion was the major route of exposure (98%) followed by inhalation (1.96%). The majority 33(32.4%) of cases were of Organophosphorus poisoning followed by 17(16.7%) cases of Rodenticide poisoning. The main symptoms were nausea and vomiting in 90(88.2%) cases. Convulsions were noted in 3(2.9%) patients. Gastric lavage was done for 92(90.19%). 8 patients (7.84%) were needed mechanical ventilation. 7 patients (6.86%) were needed vasoactive drugs. The rate of mortality was 8.82%. The aluminium phosphide poisoning was responsible for 44.4% deaths. Conclusion: Study revealed the high mortality associated with acute poisoning. Appropriate approach towards poisoning at tertiary care center and prevention remains the best strategy for reducing morbidity and mortality.

Keywords

• acute poisoning
• intensive care unit
• mortality
• organophosphorus compound