BIOLOGICAL ACTIVITY OF AROYLHYDRAZIDES 1,4-DICARBOXYLIC ACIDS

Abstract

Anthelmintic, insecticidal activities and influence on hemostasis of aroylhydrazides 1,4-dicarboxylic acids were investigated. Anthelmintic activity was investigated for 8 compounds, including three substances showed effect that exceed effect of the standard (Pyrantelum). Insecticidal activity was investigated for 4 hydrazides 1,4-dicarboxylic acids, all compounds are inactive. Compounds that were tested for hemostasis do not possess anticoagulant activity. They are characterized by a hemostatic effect which is lower than activity of Etamsylate.

Keywords

• aroylhydrazide 1
• 4-decarboxylic acids
• antihelminthic activity
• insecticidal activity
• anticoagulating activity
• local anesthetizing activity