Терапевтический архив (Nov 2016)

Use of succinate-containing agents in the treatment of infectious diseases

  • E O Tikhonova,
  • E P Lyapina,
  • A A Shul’dyakov,
  • S A Satarova

DOI
https://doi.org/10.17116/terarkh20168811121-127
Journal volume & issue
Vol. 88, no. 11
pp. 121 – 127

Abstract

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The review gives data that reveal the role of succinic acid in providing cells with energy and oxygen under hypoxic conditions. It presents the results of clinical and experimental studies to evaluate the efficacy of succinate-containing drugs in the combination therapy of infectious diseases. The spectrum of biological effects of these drugs, which is provided by the synergy of their active ingredients, is considered.

Keywords