Heart Failure With Preserved Ejection Fraction and Obesity

Abstract

This report describes a case of heart failure with preserved ejection fraction in a post-menopausal woman with obesity. The case highlights a metabolic phenotype of heart failure with preserved ejection fraction that commonly manifests in women, with the discussion focusing on pathophysiology, mechanistic pathways, and potential targeted therapeutic strategies. (Level of Difficulty: Intermediate.)

Keywords

• heart failure with preserved ejection fraction
• HFpEF
• obesity
• women