A CLINICAL EXPERIENCE OF METHOTREXATE USE IN TREATMENT OF PATIENT WITH JUVENILE OLIGOARTHRITIS

Abstract

This article presents clinical case of early manifestation of juvenile oligoarthritis with rapid contracture and destructive joint changes formation. Methotrexate was administered IM 15 mg/m2 once a week. After 3 months of treatment — acute inflammatory changes in the joint were relieved as well as arthralgias, morning stiffness and there was a decrease in laboratory markers of the disease. After 6 months full motion range of the joint was achieved and contracture relieved. Remission is maintained for the last 12 months.Key words: children, juvenile arthritis, methotrexate. (Voprosy sovremennoi pediatrii — Current Pediatrics. — 2011; 10 (6): 191–197)

Keywords

• children
• juvenile arthritis
• methotrexate