GMS Medizinische Informatik, Biometrie und Epidemiologie (May 2020)

Fisher’s significance test: A gentle introduction

  • Stang, Andreas,
  • Kowall, Bernd

DOI
https://doi.org/10.3205/mibe000206
Journal volume & issue
Vol. 16, no. 1
p. Doc03

Abstract

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The p-value is often misunderstood and, for example, misinterpreted as a probability for the correctness of the null hypothesis. The aim of this article is to first explain the definition of the p-value. Determining the p-value requires knowledge of a probability function. How an appropriate statistical model is selected and how the p-value is determined using this model, the null hypothesis and the empirical data is explained using the t-distribution. When interpreting the p-value obtained in this way, two incompatible statistical schools of thought are confronted: the orthodox Neyman-Pearson hypothesis test, which amounts to a decision between the null hypothesis and a complementary alternative hypothesis, and Fisher’s significance test, in which no alternative hypothesis is formulated and in which the smaller the p-value, the greater the evidence against the null hypothesis. The amount ends with some critical remarks about the handling of p-values.

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