Nature Communications (Feb 2018)

Generalized leaky integrate-and-fire models classify multiple neuron types

  • Corinne Teeter,
  • Ramakrishnan Iyer,
  • Vilas Menon,
  • Nathan Gouwens,
  • David Feng,
  • Jim Berg,
  • Aaron Szafer,
  • Nicholas Cain,
  • Hongkui Zeng,
  • Michael Hawrylycz,
  • Christof Koch,
  • Stefan Mihalas

DOI
https://doi.org/10.1038/s41467-017-02717-4
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15

Abstract

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Simplified neuron models, such as generalized leaky integrate-and-fire (GLIF) models, are extensively used in network modeling. Here the authors systematically generate and compare GLIF models of varying complexity for their ability to classify cell types in the Allen Cell Types Database and faithfully reproduce spike trains.