Farmacja Polska (Dec 2020)

Review of drugs currently used to treat pain in osteoarthritis

  • Katarzyna Kwas,
  • Marcin Mostowy,
  • Pawel Kozielewicz,
  • Joanna J. Sajkowska-Kozielewicz

DOI
https://doi.org/10.32383/farmpol/131175
Journal volume & issue
Vol. 76, no. 10
pp. 592 – 599

Abstract

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Pain associated with musculoskeletal system disorders is often the reason why patients seek medical advice. This is also the case for osteoarthritis where the pain is the first and dominant symptom which reduces the quality of life. Therefore, pain reduction and improvement in joint mobility should be the objectives of therapy. Pharmacotherapy in osteoarthritis is based on paracetamol, NSAIDS, SYSADOA or opioids. Additionally, injections with corticosteroids, platelet-rich plasma or hyaluronic acid, as well as sesamin- and polyphenol-rich diet, have proven effective. It needs to be noted that optimal therapy in osteoarthritis should consist of pharmacotherapy combined with non-pharmacological methods, such as physiotherapy, bodyweight monitoring, well-balanced diet and education. Pain associated with musculoskeletal system disorders is often the reason why patients seek medical advice. This is also the case for osteoarthritis where the pain is the first and dominant symptom which reduces the quality of life. Therefore, pain reduction and improvement in joint mobility should be the objectives of therapy. Pharmacotherapy in osteoarthritis is based on paracetamol, NSAIDS, SYSADOA or opioids. Additionally, injections with corticosteroids, platelet-rich plasma or hyaluronic acid, as well as sesamin- and polyphenol-rich diet, have proven effective. It needs to be noted that optimal therapy in osteoarthritis should consist of pharmacotherapy combined with non-pharmacological methods, such as physiotherapy, bodyweight monitoring, well-balanced diet and education. Pain associated with musculoskeletal system disorders is often the reason why patients seek medical advice. This is also the case for osteoarthritis where the pain is the first and dominant symptom which reduces the quality of life. Therefore, pain reduction and improvement in joint mobility should be the objectives of therapy. Pharmacotherapy in osteoarthritis is based on paracetamol, NSAIDS, SYSADOA or opioids. Additionally, injections with corticosteroids, platelet-rich plasma or hyaluronic acid, as well as sesamin- and polyphenol-rich diet, have proven effective. It needs to be noted that optimal therapy in osteoarthritis should consist of pharmacotherapy combined with non-pharmacological methods, such as physiotherapy, bodyweight monitoring, well-balanced diet and education.

Keywords