eLife
(Dec 2023)
Probing ligand selectivity in pathogens
Bryan VanSchouwen,
Giuseppe Melacini
Affiliations
Bryan VanSchouwen
ORCiD
Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Canada
Giuseppe Melacini
ORCiD
Department of Chemistry and Chemical Biology, and the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada
DOI
https://doi.org/10.7554/eLife.94720
Journal volume & issue
Vol. 12
Abstract
Read online
Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other organisms?
Keywords
Published in eLife
ISSN
2050-084X (Online)
Publisher
eLife Sciences Publications Ltd
Country of publisher
United Kingdom
LCC subjects
Medicine
Science: Biology (General)
Website
https://elifesciences.org
About the journal
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